Vanguard

Maternal Antibodies

Vanguard^® Plus CPV overcomes maternal antibodies to produce a strong immune response.

• Puppies born to dams with immunity to CPV are initially protected by maternal antibodies acquired through colostrum.
• These maternal antibodies can interfere with the effectiveness of a vaccine-induced immunity.
• The average half-life of CPV maternal antibodies is approximately 10 days.¹

CPV hemagglutination inhibition titers ≥ 1:80 protect puppies from infection, but titers between 1:40 and 1:80 are not protective and may interfere with vaccination.²

 

1. Carmichael LE. Immunization strategies in puppies — why failures? Compend Contin Educ Pract Vet 1983;5:1043-1051.

2. Carmichael LE, Joubert JC, et al. A modified live canine parvovirus vaccine. II. Immune response. Cornell Vet 1981;71:408-427.

All brands are the property of Pfizer Inc., its affiliates and/or its licensors. Copyright © 2009 Pfizer Inc.

The product information provided in this site is intended only for residents of the United States. The products discussed herein may have different product label indications in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace consultation with your veterinarian. All decisions regarding animal health care must be made with a veterinarian, considering the unique characteristics of the patient.